28-year-old Joe Rodon picked up a serious hamstring injury in last weekend's 1-1 Premier League draw with Brentford, ruling him out for eight to 10 weeks.
Daniel Farke called it a big blow for the key centre-back, who started Leeds' first two unbeaten matches, adding pressure ahead of Saturday's trip to Brighton. Rodon could be out until November and miss at least the next eight matches.
The team eyes options like new signing Melvin Bard and James Justin to fill the gap, while Fantasy Premier League managers scramble for alternatives in Rodon's £4.5m price range.